At Will Bloom's wedding party in 2000, his father Edward recalls the day Will was born, claiming he caught an enormous catfish using his wedding ring as bait. Will, having heard these stories all his life, believes them to be lies and falls out with his father.
Three years later in 2003, Edward has cancer, so Will and his pregnant French wife Joséphine return to the town of Ashton, Alabama, to spend time with him. During the plane ride, Will recalls a story of Edward's childhood encounter with a witch, who shows him his death in her glass eye. Edward, in spite of his illness, continues to tell the story of his life to Will and Joséphine. He claims to have once been bedridden for three years due to his rapid growth spurts. He then became a locally famous sportsman before being driven by his ambition to leave his hometown.