FBI agent Malcolm Turner (Martin Lawrence) is elated to learn that his stepson, Trent Pierce (Brandon T. Jackson), has been accepted to attend Duke University in Durham, North Carolina. However, Trent is uninterested and instead wants Malcolm to sign a recording contract for him since he is underage. When Malcolm refuses, Trent's best friends encourage him to ambush Malcolm on the job in order to obtain the signature.
Malcolm, in an attempt to capture Russian gang member Chirkoff (Tony Curran), uses an informant named Canetti to deliver a flash drive to the gang, while Trent attempts to ambush Malcolm on the job. Canetti (Max Casella) reveals that the flash drive is empty and a duplicate is hidden with a friend at the Georgia Girls School for the Arts.