Resident Evil: Afterlife

One year after the events of Extinction, Alice (Milla Jovovich) and her clones lead the assault to attack Umbrella HQ, located in Tokyo, slaying the entire branch except for Albert Wesker (Shawn Roberts), who escapes in a tiltrotor plane and detonates a bomb that leaves a massive sinkhole. The real Alice boarded beforehand and attempts to execute Wesker, only for him to inject her with an anti-virus to remove her superhuman abilities. Wesker is revealed to have used the T-virus to gain his own superhuman abilities and prepares to kill Alice before the autopilot crashes the plane into the mountains, and only Alice survives.