Dana Scully, a former FBI Special Agent, is now a staff physician at a Catholic hospital; she is treating Christian, a young boy with symptoms similar to Sandhoff disease. FBI Special Agent Mosely Drummy approaches Scully for help in locating her former partner, Fox Mulder, who has been in hiding as a fugitive for several years. Drummy states that the FBI will call off its manhunt for Mulder if he helps investigate the disappearances of several women in West Virginia, the latest of whom is a young FBI Special Agent named Monica Bannan. Scully agrees and convinces a reluctant Mulder to help.