Isle of Dogs

An outbreak of canine influenza spreads throughout the (fictitious) city of Megasaki with the risk of becoming contagious to humans. The city's authoritarian mayor, Kenji Kobayashi, ratifies an official decree banishing all dogs to Trash Island, which is immediately approved despite the insistence of Professor Watanabe, the mayor's political opponent, who states he is close to creating a cure. The first deported canine is a white and black-spotted dog named Spots Kobayashi, who served as the bodyguard dog of 12-year-old orphan Atari Kobayashi, the mayor's distant nephew and ward.