Investment banker cubicle worker Harold Lee is pressured by his colleagues to do their work while they leave for the weekend. Meanwhile, his roommate Kumar Patel attends a medical school interview, where he is highly qualified but intentionally botches it to avoid getting accepted. Harold is attracted to his neighbor, Maria, but is unable to admit his feelings. After smoking marijuana and seeing an advertisement for White Castle, the pair decide to get its hamburgers. After traveling to the nearest White Castle in New Brunswick, they find it replaced by "Burger Shack". The drive-thru employee informs them of another White Castle in Cherry Hill.