Sam and Dean Winchester go up against all kinds of monsters - but what about Harry Potter monsters in the wizarding world?

Which Marvel superheroes could Supernatural's Sam & Dean beat? Iron Man? The Hulk? And more importantly, which superheroes are too much for them?

Sam and Dean Winchester have defeated pretty much every bad guy on Supernatural, but would they win or lose against the Justice League Dark monsters?

Sam and Dean Winchester are the most formidable demon hunters in the world, but which Death Eaters could they take, and which would defeat them?

Sam and Dean Winchester could probably give Buffy Summers a run for her money, but how would they fare against these classic BtVS demons?

From cursed objects to fan-favorite characters returning, we explore how Sam and Dean could find a way to actually defeat God on Supernatural.

How would the Winchesters fare in the Witcher world? These are 5 Witcher monsters that the boys could certainly beat, along with 5 they couldn't.

On Supernatural, Sam and Dean Winchester are used to saving the day. But how would they fare against DC Comics' superheroes like Superman or Batman?

Sam and Dean Winchester have beat many evil demons on Supernatural, but how would they fare in the Doctor Who universe? We say it'd be a mixed bag.

We pit Supernatural's Sam & Dean Winchester against the vampires from The Vampire Diaries to see who would come out on top in each pairing.

Lucifer may have turned out not to be the big bad in Supernatural but he was far from heroic. Here are the worst things he did to the Winchesters.

Daybreak season 1's ending appears to set up Josh's lost love Sam Dean as the main villain for season 2 - but has she actually done anything wrong?

Sam and Dean Winchester saved the world yet again, and their actions have huge implications not just for Hell, but for their half-brother, Adam.

Family is the most important thing for Sam and Dean, and certain supporting characters from Supernatural have reached that level of closeness.

With season 15 officially marking the end of Supernatural, the stars of the show gifted one lucky fan a replica of their signature Chevy Impala.

Sam and Dean Winchester have been the sole main characters of Supernatural for 14 seasons now. While others have been upgraded to the main cast, only Sam and Dean appear in every episode in each season. This means they can’t be killed off for real from the show; however, you’ll be surprised to know Sam and Dean have the most deaths of any character we’ve seen on Supernatural.